标签：COOH-PEG-SIL 羧基PEG硅烷

COOH-PEG-SIL 羧基PEG硅烷

COOH-PEG-SIL 羧基PEG硅烷   Silane PEG acid

金畔生物  Laysan  Nanocs修饰性PEG

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Nanocs–COOH-PEG-SIL 羧基PEG硅烷  Silane PEG acid

PG2-CASL-5k Silane PEG acid, Silane-PEG-COOH 5000 Da 100 mg $285.00
PG2-CASL-3k Silane PEG acid, Silane-PEG-COOH 3400 Da 100 mg $325.00
PG2-CASL-2k Silane PEG acid, Silane-PEG-COOH 2000 Da 100 mg $385.00
PG2-CASL-10k Silane PEG acid, Silane-PEG-COOH 10000 Da 100 mg $385.00
PG2-CASL-1k Silane-PEG-COOH 1000 Da 100 mg $425.00
PG2-CASL-600 Silane-PEG-COOH 600 Da 100 mg $485.00

Nanocs–COOH-PEG-SIL 羧基PEG硅烷套装  Silane PEG acid

P2P-CASL-4 Silane-PEG-COOH Pack 4 2 KD, 3 KD, 5 KD, 10 KD 25 mg each $345.00

Description:

Ethoxy or methoxyl silane functionalized polyethylene glycol, silane PEG (PEG-Si) is a surface reactive PEG derivative that can be used to modify glass, silica and other surfaces via the reaction between hydroxyl group and ethoxyl/methoxyl silane. Pegylation can greatly suppress the non-specific binding of charged molecules to the modified surfaces. And they have wide applications for medica device, biomems or biocompatible material development.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, desiccated. Silane PEG tends to hydrolyze from moisture. Avoid frequent thaw and frozen.

Reaction Procedures:

Generally, silane PEG is first dissolved in a mixture of ethanol/water solution, then allow the solution to contact with oxidized glass or silica surface for 30 min to 2 hours. Under this condition, silane PEG should bind to the material covalently.

Materials Required:

  • Pegylation solution: Ethanol/water (w/w, 95%/5%);
  • Silane PEG stock solution, 10~50 mg/mL in pegylation solution, prepare in fresh.
  • Washing solution: Distilled water.

Reaction Steps:

1. Dissolve targeted materials in Pegylation buffer.

2. Add silane PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of silane PEG needed for optimal conjugation;

3. Allow mixture agitates at room temperature for 30 min at room temperature or 2 hours at 4 -20 0C.

4. Wash out unreacted materials either by distilled water.